irritate

Verb
  1. Cause annoyance in;
    Disturb, especially by minor irritations (synset 201791774)
    "Mosquitoes buzzing in my ear really bothers me"; "It irritates me that she never closes the door after she leaves"
  2. Excite to an abnormal condition, or chafe or inflame (synset 200063062)
    "Aspirin irritates my stomach"
  3. Excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus (synset 200504796)
    "irritate the glands of a leaf"

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